Performance of Candida Real-time Polymerase Chain Reaction, b-D-Glucan Assay, and Blood Cultures in the Diagnosis of Invasive Candidiasis
نویسندگان
چکیده
M. Hong Nguyen,1 Mark C. Wissel,2 Ryan K. Shields,1 Martin A. Salomoni,2 Binghua Hao,1 Ellen G. Press,1 Ryan M. Shields,2 Shaoji Cheng,1 Dimitra Mitsani,1 Aniket Vadnerkar,1 Fernanda P. Silveira,1 Steven B. Kleiboeker,2 and Cornelius J. Clancy1,3 1Department of Medicine, University of Pittsburgh, Pennsylvania; 2Viracor-IBT Laboratories, Lee's Summit, Missouri; and 3Department of Medicine, VA Pittsburgh Healthcare System, Pennsylvania
منابع مشابه
Performance of Candida real-time polymerase chain reaction, β-D-glucan assay, and blood cultures in the diagnosis of invasive candidiasis.
BACKGROUND The sensitivity of blood cultures for diagnosing invasive candidiasis (IC) is poor. METHODS We performed a validated Candida real-time polymerase chain reaction (PCR) and the Fungitell 1,3-β-D-glucan (BDG) assay on blood samples collected from prospectively identified patients with IC (n = 55) and hospitalized controls (n = 73). Patients with IC had candidemia (n = 17), deep-seated...
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